Internal combustion engines are poised for dramatic breakthroughs in improving efficiency with lower emissions, thanks in part to low-temperature combustion regimes. Such regimes show great efficiency and emissions potential, but they present optimization and control challenges that must be addressed before they enter the engine mainstream. Caterpillar Inc. (Cat), Peoria, Ill., recognizing that we are entering an age of high-fidelity engine modeling, turned to U.S. Department of Energy’s Argonne National Laboratory and its Virtual Engine Research Institute and Fuels Initiative (VERIFI), where experts are developing new engine combustion models that incorporate accurate descriptions of two-phase flows, chemistry, transport phenomena and device geometries to provide predictive simulations of engine and fuel performance To read further, please visit http://www.anl.gov/articles/caterpillar-argonne-undertake-cooperative-virtual-engine-design-control-project .